Murillo, Miguel M

Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism. [electronic resource] - The Biochemical journal Jul 2007 - 251-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1470-8728

10.1042/BJ20061846 doi


Acetophenones--pharmacology
Animals
Anthracenes--pharmacology
Benzamides--pharmacology
Chromones--pharmacology
Dioxoles--pharmacology
Enzyme Activation--drug effects
Epidermal Growth Factor--metabolism
ErbB Receptors--metabolism
Extracellular Signal-Regulated MAP Kinases--metabolism
Flavonoids--pharmacology
Heparin-binding EGF-like Growth Factor
Hepatocytes--enzymology
Humans
Imidazoles--pharmacology
Intercellular Signaling Peptides and Proteins
Morpholines--pharmacology
NADH, NADPH Oxidoreductases--biosynthesis
NADPH Oxidase 1
NADPH Oxidase 4
NADPH Oxidases--antagonists & inhibitors
NF-kappa B--physiology
Onium Compounds--pharmacology
Peptides--pharmacology
Phosphatidylinositol 3-Kinases--metabolism
Proto-Oncogene Proteins c-akt--metabolism
Quinazolines
Rats
Reactive Oxygen Species--pharmacology
Transforming Growth Factor beta--physiology
Tyrphostins--pharmacology
Up-Regulation
rac1 GTP-Binding Protein--biosynthesis