TY - GEN AU - Lawson,Brian R AU - Manenkova,Yulia AU - Ahamed,Jasimuddin AU - Chen,Xiaoru AU - Zou,Jian-Ping AU - Baccala,Roberto AU - Theofilopoulos,Argyrios N AU - Yuan,Chong TI - Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system SN - 0022-1767 PY - 2007///0521 KW - Adenine KW - analogs & derivatives KW - Adenosylhomocysteinase KW - antagonists & inhibitors KW - Animals KW - Autoimmune Diseases KW - drug therapy KW - Butyrates KW - pharmacology KW - CD4-Positive T-Lymphocytes KW - immunology KW - Calcium KW - metabolism KW - Down-Regulation KW - Encephalomyelitis, Autoimmune, Experimental KW - Enzyme Inhibitors KW - therapeutic use KW - Female KW - Humans KW - Jurkat Cells KW - Lymphocyte Activation KW - drug effects KW - Methylation KW - Mice KW - Proto-Oncogene Proteins c-vav KW - Receptors, Antigen, T-Cell KW - physiology KW - Signal Transduction N1 - Publication Type: Journal Article UR - https://doi.org/10.4049/jimmunol.178.8.5366 ER -