TY - GEN AU - Waiboci,Lilian W AU - Ahmed,Chulbul M AU - Mujtaba,Mustafa G AU - Flowers,Lawrence O AU - Martin,James P AU - Haider,Mohammed I AU - Johnson,Howard M TI - Both the suppressor of cytokine signaling 1 (SOCS-1) kinase inhibitory region and SOCS-1 mimetic bind to JAK2 autophosphorylation site: implications for the development of a SOCS-1 antagonist SN - 0022-1767 PY - 2007///0521 KW - Amino Acid Sequence KW - Animals KW - Cell Line KW - Humans KW - Interferon-Stimulated Gene Factor 3 KW - metabolism KW - Interferon-gamma KW - pharmacology KW - Janus Kinase 2 KW - Lymphocyte Activation KW - drug effects KW - Macrophage Activation KW - Mice KW - Mice, Inbred C57BL KW - Molecular Sequence Data KW - Peptide Fragments KW - Phosphorylation KW - Protein Kinase Inhibitors KW - STAT3 Transcription Factor KW - Suppressor of Cytokine Signaling 1 Protein KW - Suppressor of Cytokine Signaling Proteins KW - antagonists & inhibitors KW - src Homology Domains N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.4049/jimmunol.178.8.5058 ER -