Waiboci, Lilian W

Both the suppressor of cytokine signaling 1 (SOCS-1) kinase inhibitory region and SOCS-1 mimetic bind to JAK2 autophosphorylation site: implications for the development of a SOCS-1 antagonist. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Apr 2007 - 5058-68 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

0022-1767

10.4049/jimmunol.178.8.5058 doi


Amino Acid Sequence
Animals
Cell Line
Humans
Interferon-Stimulated Gene Factor 3--metabolism
Interferon-gamma--pharmacology
Janus Kinase 2--metabolism
Lymphocyte Activation--drug effects
Macrophage Activation--drug effects
Mice
Mice, Inbred C57BL
Molecular Sequence Data
Peptide Fragments--pharmacology
Phosphorylation
Protein Kinase Inhibitors--metabolism
STAT3 Transcription Factor--metabolism
Suppressor of Cytokine Signaling 1 Protein
Suppressor of Cytokine Signaling Proteins--antagonists & inhibitors
src Homology Domains