Molecular signaling mediated by angiotensin II type 1A receptor blockade leading to attenuation of renal dysfunction-associated heart failure. [electronic resource]
- Journal of cardiac failure Mar 2007
- 155-62 p. digital
Publication Type: Journal Article
1532-8414
10.1016/j.cardfail.2006.11.005 doi
Angiotensin II Type 1 Receptor Blockers--therapeutic use Animals Antihypertensive Agents--therapeutic use Blood Urea Nitrogen Blotting, Western Creatinine--blood DNA--genetics Disease Models, Animal Heart Failure--drug therapy Immunohistochemistry Kidney Failure, Chronic--complications Male Matrix Metalloproteinase 2--biosynthesis Matrix Metalloproteinase 9--biosynthesis Mice Mice, Inbred C57BL Mice, Knockout Myocardium--metabolism Nephrectomy--adverse effects Oxidative Stress--genetics Receptor, Angiotensin, Type 1--blood Signal Transduction--physiology Tetrazoles--therapeutic use Tissue Inhibitor of Metalloproteinase-1--genetics Transforming Growth Factor beta1--biosynthesis Treatment Outcome Up-Regulation--drug effects Valine--analogs & derivatives Valsartan Ventricular Function, Left--drug effects