Shimoishi, Kazuki <br/><br/>
An oral adsorbent, AST-120 protects against the progression of oxidative stress by reducing the accumulation of indoxyl sulfate in the systemic circulation in renal failure.  [electronic resource] 

 -  Pharmaceutical research  Jul 2007 
 - 1283-9 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0724-8741 
<br/><br/><label>Standard No.: </label>10.1007/s11095-007-9248-x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Animals<br/>Antioxidants--administration & dosage<br/>Biomarkers--blood<br/>Carbon--administration & dosage<br/>Cells, Cultured<br/>Disease Models, Animal<br/>Dose-Response Relationship, Drug<br/>Endothelial Cells--drug effects<br/>Gene Expression--drug effects<br/>Humans<br/>Indican--blood<br/>Kidney Failure, Chronic--drug therapy<br/>Male<br/>Nephrectomy<br/>Organic Anion Transport Protein 1--genetics<br/>Oxidation-Reduction<br/>Oxidative Stress--drug effects<br/>Oxides--administration & dosage<br/>RNA, Messenger--metabolism<br/>Rats<br/>Rats, Wistar<br/>Reactive Oxygen Species--metabolism<br/>Serum Albumin--metabolism<br/>Time Factors<br/>Transforming Growth Factor beta1--genetics