TY  - GEN
AU  - Maillet,Emeline L
AU  - Pellegrini,Nadia
AU  - Valant,Celine
AU  - Bucher,Bernard
AU  - Hibert,Marcel
AU  - Bourguignon,Jean-Jacques
AU  - Galzi,Jean-Luc
TI  - A novel, conformation-specific allosteric inhibitor of the tachykinin NK2 receptor (NK2R) with functionally selective properties
SN  - 1530-6860
PY  - 2007///0815
KW  - Allosteric Regulation
KW  - Aminoacetonitrile
KW  - analogs & derivatives
KW  - Animals
KW  - Calcium
KW  - metabolism
KW  - Calcium Signaling
KW  - drug effects
KW  - Cell Line
KW  - Cyclic AMP
KW  - biosynthesis
KW  - Cyclic AMP-Dependent Protein Kinases
KW  - Fluorescence Resonance Energy Transfer
KW  - Fluorescent Dyes
KW  - analysis
KW  - Genes, Reporter
KW  - Humans
KW  - Kidney
KW  - Kinetics
KW  - Naphthalenes
KW  - chemical synthesis
KW  - Neurokinin A
KW  - Protein Binding
KW  - Protein Conformation
KW  - Rats
KW  - Receptors, Neurokinin-2
KW  - antagonists & inhibitors
KW  - Recombinant Fusion Proteins
KW  - Second Messenger Systems
KW  - Structure-Activity Relationship
KW  - Substrate Specificity
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1096/fj.06-7683com
ER  -