TY  - GEN
AU  - Latchoumycandane,Calivarathan
AU  - Goh,Catherine W
AU  - Ong,Michie M K
AU  - Boelsterli,Urs A
TI  - Mitochondrial protection by the JNK inhibitor leflunomide rescues mice from acetaminophen-induced liver injury
SN  - 0270-9139
PY  - 2007///0329
KW  - Acetaminophen
KW  - adverse effects
KW  - Analgesics, Non-Narcotic
KW  - Animals
KW  - Apoptosis
KW  - physiology
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Immunity, Innate
KW  - drug effects
KW  - Isoxazoles
KW  - Leflunomide
KW  - Liver
KW  - MAP Kinase Kinase 4
KW  - antagonists & inhibitors
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mitochondria
KW  - Necrosis
KW  - pathology
KW  - Peroxynitrous Acid
KW  - metabolism
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - bcl-X Protein
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1002/hep.21475
ER  -