TY  - GEN
AU  - Parikh,S
AU  - Ouedraogo,J-B
AU  - Goldstein,J A
AU  - Rosenthal,P J
AU  - Kroetz,D L
TI  - Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa
SN  - 0009-9236
PY  - 2007///0911
KW  - Alkynes
KW  - Amodiaquine
KW  - analogs & derivatives
KW  - Antimalarials
KW  - metabolism
KW  - Aryl Hydrocarbon Hydroxylases
KW  - genetics
KW  - Benzoxazines
KW  - Burkina Faso
KW  - Chromatography, High Pressure Liquid
KW  - Cyclopropanes
KW  - Cytochrome P-450 CYP2C8
KW  - Dose-Response Relationship, Drug
KW  - Drug Interactions
KW  - Enzyme Inhibitors
KW  - Genotype
KW  - HIV Protease Inhibitors
KW  - Humans
KW  - Lopinavir
KW  - Malaria, Falciparum
KW  - drug therapy
KW  - Models, Biological
KW  - Polymorphism, Genetic
KW  - Pyridines
KW  - Pyrimidinones
KW  - Pyrones
KW  - Reverse Transcriptase Inhibitors
KW  - Saquinavir
KW  - Spectrophotometry, Ultraviolet
KW  - Sulfonamides
KW  - Treatment Outcome
KW  - Trimethoprim
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
UR  - https://doi.org/10.1038/sj.clpt.6100122
ER  -