TY  - GEN
AU  - Farid,N A
AU  - Payne,C D
AU  - Small,D S
AU  - Winters,K J
AU  - Ernest,C S
AU  - Brandt,J T
AU  - Darstein,C
AU  - Jakubowski,J A
AU  - Salazar,D E
TI  - Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently
SN  - 0009-9236
PY  - 2007///0515
KW  - Adult
KW  - Area Under Curve
KW  - Clopidogrel
KW  - Cross-Over Studies
KW  - Cytochrome P-450 CYP3A Inhibitors
KW  - Double-Blind Method
KW  - Drug Interactions
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Female
KW  - Humans
KW  - Ketoconazole
KW  - Male
KW  - Middle Aged
KW  - Piperazines
KW  - administration & dosage
KW  - Platelet Aggregation
KW  - drug effects
KW  - Platelet Aggregation Inhibitors
KW  - Prasugrel Hydrochloride
KW  - Thiophenes
KW  - Ticlopidine
N1  - Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/sj.clpt.6100139
ER  -