Spitzer, Martin S

Comparative antiproliferative and cytotoxic profile of bevacizumab (Avastin), pegaptanib (Macugen) and ranibizumab (Lucentis) on different ocular cells. [electronic resource] - Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Dec 2007 - 1837-42 p. digital

Publication Type: Comparative Study; Journal Article

0721-832X

10.1007/s00417-007-0568-7 doi


Angiogenesis Inhibitors--toxicity
Animals
Antibodies, Monoclonal--toxicity
Antibodies, Monoclonal, Humanized
Aptamers, Nucleotide--toxicity
Bevacizumab
Cell Proliferation--drug effects
Cell Survival
Cells, Cultured
Choroid--blood supply
DNA--biosynthesis
Endothelium, Vascular--drug effects
Enzyme-Linked Immunosorbent Assay
Humans
Immunohistochemistry
Materials Testing
Pigment Epithelium of Eye--drug effects
Ranibizumab
Rats
Retinal Ganglion Cells--drug effects
Swine
Vascular Endothelial Growth Factor A--antagonists & inhibitors
Vascular Endothelial Growth Factor Receptor-1--metabolism
Vascular Endothelial Growth Factor Receptor-2--metabolism
von Willebrand Factor--metabolism