TY - GEN AU - Chioato,Lucimara AU - Aragão,Elisangela Aparecida AU - Lopes Ferreira,Tatiana AU - Medeiros,Alexandra Ivo de AU - Faccioli,Lúcia Helena AU - Ward,Richard J TI - Mapping of the structural determinants of artificial and biological membrane damaging activities of a Lys49 phospholipase A2 by scanning alanine mutagenesis SN - 0006-3002 PY - 2007///0607 KW - Alanine KW - metabolism KW - Animals KW - Bothrops KW - Calcium KW - Cell Membrane KW - drug effects KW - Cell Membrane Permeability KW - Cells, Cultured KW - Creatine Kinase KW - blood KW - Escherichia coli KW - Liposomes KW - Lysine KW - Male KW - Membranes, Artificial KW - Mice KW - Microbial Sensitivity Tests KW - Models, Molecular KW - Mutagenesis KW - Mutant Proteins KW - Phospholipases A KW - chemistry KW - Phospholipases A2 KW - Protein Structure, Secondary KW - Snake Venoms KW - enzymology KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bbamem.2007.01.023 ER -