TY  - GEN
AU  - Hinke,S A
AU  - Martens,G A
AU  - Cai,Y
AU  - Finsi,J
AU  - Heimberg,H
AU  - Pipeleers,D
AU  - Van de Casteele,M
TI  - Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer
SN  - 0007-1188
PY  - 2007///0524
KW  - AMP-Activated Protein Kinases
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Biguanides
KW  - antagonists & inhibitors
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Dose-Response Relationship, Drug
KW  - Electron Transport
KW  - Electron Transport Complex I
KW  - Electron Transport Complex II
KW  - Enzyme Activation
KW  - Glucose
KW  - metabolism
KW  - Hypoglycemic Agents
KW  - Insulin-Secreting Cells
KW  - Metformin
KW  - toxicity
KW  - Mice
KW  - Mitochondria
KW  - Multienzyme Complexes
KW  - NADP
KW  - Oxidation-Reduction
KW  - Phenformin
KW  - Phosphorylation
KW  - Protein Serine-Threonine Kinases
KW  - Rats
KW  - Succinates
KW  - Tetrazolium Salts
KW  - Thiazoles
KW  - Time Factors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/sj.bjp.0707189
ER  -