A type 1 diabetes subgroup with a female bias is characterised by failure in tolerance to thyroid peroxidase at an early age and a strong association with the cytotoxic T-lymphocyte-associated antigen-4 gene. [electronic resource]
- Diabetologia Apr 2007
- 741-6 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0012-186X
10.1007/s00125-007-0603-6 doi
Adolescent Age of Onset Alleles Antigens, CD--genetics Antigens, Differentiation--genetics Autoantigens--chemistry Autoimmunity CTLA-4 Antigen Child Child, Preschool Diabetes Mellitus, Type 1--diagnosis Female Genetic Variation Humans Infant Infant, Newborn Iodide Peroxidase--chemistry Iron-Binding Proteins--chemistry Male Odds Ratio Polymorphism, Single Nucleotide Protein Tyrosine Phosphatase, Non-Receptor Type 1 Protein Tyrosine Phosphatase, Non-Receptor Type 22 Protein Tyrosine Phosphatases--genetics Sex Factors