TY - GEN AU - Wichmann,Christian AU - Chen,Linping AU - Heinrich,Markus AU - Baus,Daniela AU - Pfitzner,Edith AU - Zörnig,Martin AU - Ottmann,Oliver G AU - Grez,Manuel TI - Targeting the oligomerization domain of ETO interferes with RUNX1/ETO oncogenic activity in t(8;21)-positive leukemic cells SN - 0008-5472 PY - 2007///0412 KW - Amino Acid Sequence KW - Cell Line, Tumor KW - Chromosomes, Human, Pair 21 KW - Chromosomes, Human, Pair 8 KW - Core Binding Factor Alpha 2 Subunit KW - genetics KW - DNA-Binding Proteins KW - antagonists & inhibitors KW - HL-60 Cells KW - HeLa Cells KW - Humans KW - Jurkat Cells KW - Leukemia KW - Molecular Sequence Data KW - Oncogene Proteins, Fusion KW - metabolism KW - Peptide Fragments KW - pharmacology KW - Protein Structure, Tertiary KW - Proto-Oncogene Proteins KW - RUNX1 Translocation Partner 1 Protein KW - Transcription Factors KW - Transcriptional Activation KW - drug effects KW - Translocation, Genetic N1 - Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-06-3360 ER -