PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms. [electronic resource]
- Developmental biology May 2007
- 28-39 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0012-1606
10.1016/j.ydbio.2007.01.031 doi
Animals Blotting, Western Cell Differentiation--physiology Cell Line Cell Proliferation Chondrocytes--metabolism Cyclic AMP-Dependent Protein Kinases Gene Expression Regulation, Developmental--physiology Growth Plate--cytology Hedgehog Proteins--metabolism Immunohistochemistry In Situ Nick-End Labeling Kruppel-Like Transcription Factors--genetics Mice Mice, Knockout Nerve Tissue Proteins--genetics Parathyroid Hormone-Related Protein--metabolism Protein Serine-Threonine Kinases--metabolism Signal Transduction--physiology Zinc Finger Protein Gli2 Zinc Finger Protein Gli3