Atwell, Graham J <br/><br/>
Synthesis and structure-activity relationships for 2,4-dinitrobenzamide-5-mustards as prodrugs for the Escherichia coli nfsB nitroreductase in gene therapy.  [electronic resource] 

 -  Journal of medicinal chemistry  Mar 2007 
 - 1197-212 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm061062o  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents, Alkylating--chemical synthesis<br/>Bystander Effect<br/>Cell Line, Tumor<br/>Drug Screening Assays, Antitumor<br/>Enzyme Activation<br/>Escherichia coli Proteins--genetics<br/>Female<br/>Genetic Therapy<br/>Humans<br/>Least-Squares Analysis<br/>Male<br/>Mice<br/>Mice, Nude<br/>Multivariate Analysis<br/>Nitrogen Mustard Compounds--chemical synthesis<br/>Nitroreductases--genetics<br/>Prodrugs--chemical synthesis<br/>Quantitative Structure-Activity Relationship<br/>Transplantation, Heterologous