López-Atalaya, José P

Recombinant Desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptor-related protein-dependent mechanism without exerting neurotoxic effects. [electronic resource] - Stroke Mar 2007 - 1036-43 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1524-4628

10.1161/01.STR.0000258100.04923.84 doi


Animals
Blood-Brain Barrier--drug effects
Cattle
Cells, Cultured
Chiroptera
Coculture Techniques
Fibrinolytic Agents--pharmacokinetics
Humans
Low Density Lipoprotein Receptor-Related Protein-1--physiology
Male
Plasminogen Activators--pharmacokinetics
Rats
Rats, Sprague-Dawley
Recombinant Proteins--pharmacokinetics