TY  - GEN
AU  - Hamberg,A-K
AU  - Dahl,M-L
AU  - Barban,M
AU  - Scordo,M G
AU  - Wadelius,M
AU  - Pengo,V
AU  - Padrini,R
AU  - Jonsson,E N
TI  - A PK-PD model for predicting the impact of age, CYP2C9, and VKORC1 genotype on individualization of warfarin therapy
SN  - 0009-9236
PY  - 2007///0425
KW  - Aged
KW  - Aged, 80 and over
KW  - Aging
KW  - metabolism
KW  - Algorithms
KW  - Anticoagulants
KW  - administration & dosage
KW  - Aryl Hydrocarbon Hydroxylases
KW  - genetics
KW  - Cytochrome P-450 CYP2C9
KW  - DNA
KW  - Databases, Factual
KW  - Female
KW  - Genotype
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Mixed Function Oxygenases
KW  - Models, Statistical
KW  - Pharmacokinetics
KW  - Population
KW  - Stereoisomerism
KW  - Vitamin K Epoxide Reductases
KW  - Warfarin
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/sj.clpt.6100084
ER  -