TY - GEN AU - Doshi,Ami TI - The cost of clear skin: balancing the social and safety costs of iPLEDGE with the efficacy of Accutane (isotretinoin) SN - 0586-5964 PY - 2007///0305 KW - Abnormalities, Drug-Induced KW - prevention & control KW - Acne Vulgaris KW - drug therapy KW - Adverse Drug Reaction Reporting Systems KW - instrumentation KW - Contraindications KW - Cost-Benefit Analysis KW - Drug Approval KW - Drug and Narcotic Control KW - history KW - Female KW - Fetus KW - Guidelines as Topic KW - History, 20th Century KW - History, 21st Century KW - Humans KW - Isotretinoin KW - administration & dosage KW - Legislation, Pharmacy KW - Male KW - Maternal-Fetal Exchange KW - Pharmaceutical Services KW - standards KW - Pregnancy KW - drug effects KW - Reproductive Behavior KW - Risk Management KW - methods KW - Skin Diseases KW - Social Control Policies KW - economics KW - United States KW - United States Food and Drug Administration N1 - Publication Type: Historical Article; Journal Article ER -