The immunosuppressant FK506 promotes development of the chondrogenic phenotype in human synovial stromal cells via modulation of the Smad signaling pathway. [electronic resource]
- Osteoarthritis and cartilage Jun 2007
- 709-18 p. digital
Publication Type: Journal Article
1063-4584
10.1016/j.joca.2007.01.006 doi
Adult Cartilage, Articular--drug effects Chondrocytes--drug effects Chondrogenesis--drug effects Female Gene Expression Regulation--drug effects Humans Immunosuppressive Agents--therapeutic use Male Middle Aged Phenotype Signal Transduction--drug effects Smad Proteins--drug effects Stromal Cells--drug effects Tacrolimus--therapeutic use Transforming Growth Factor beta1--drug effects