TY - GEN AU - Martin,Matthew W AU - Newcomb,John AU - Nunes,Joseph J AU - Bemis,Jean E AU - McGowan,David C AU - White,Ryan D AU - Buchanan,John L AU - DiMauro,Erin F AU - Boucher,Christina AU - Faust,Theodore AU - Hsieh,Faye AU - Huang,Xin AU - Lee,Josie H AU - Schneider,Stephen AU - Turci,Susan M AU - Zhu,Xiaotian TI - Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties SN - 0960-894X PY - 2007///0530 KW - Amines KW - chemical synthesis KW - Animals KW - Humans KW - Inhibitory Concentration 50 KW - Lymphocyte Specific Protein Tyrosine Kinase p56(lck) KW - antagonists & inhibitors KW - Pharmacokinetics KW - Protein Kinase Inhibitors KW - Pyridines KW - Rats KW - Rats, Sprague-Dawley KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2007.01.048 ER -