TY - GEN AU - Gao,Ben-Bo AU - Clermont,Allen AU - Rook,Susan AU - Fonda,Stephanie J AU - Srinivasan,Vivek J AU - Wojtkowski,Maciej AU - Fujimoto,James G AU - Avery,Robert L AU - Arrigg,Paul G AU - Bursell,Sven-Erik AU - Aiello,Lloyd Paul AU - Feener,Edward P TI - Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation SN - 1078-8956 PY - 2007///0430 KW - Acetazolamide KW - pharmacology KW - Animals KW - Blotting, Western KW - Bradykinin Receptor Antagonists KW - Capillary Permeability KW - drug effects KW - Carbonic Anhydrase Inhibitors KW - Carbonic Anhydrases KW - metabolism KW - Complement C1 KW - antagonists & inhibitors KW - Diabetic Retinopathy KW - drug therapy KW - Eye Proteins KW - Factor XIIa KW - Humans KW - Kallikrein-Kinin System KW - physiology KW - Mass Spectrometry KW - Papilledema KW - chemically induced KW - Proteomics KW - Rats KW - Rats, Sprague-Dawley KW - Statistics, Nonparametric KW - Vitreous Body KW - enzymology N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1038/nm1534 ER -