Barnes, D J <br/><br/>
Different target range and cytotoxic specificity of adaphostin and 17-allylamino-17-demethoxygeldanamycin in imatinib-resistant and sensitive cell lines.  [electronic resource] 

 -  Leukemia  Mar 2007 
 - 421-6 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0887-6924 
<br/><br/><label>Standard No.: </label>10.1038/sj.leu.2404533  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adamantane--adverse effects<br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Benzamides<br/>Benzoquinones--adverse effects<br/>Cell Line, Transformed--drug effects<br/>Cell Line, Tumor--drug effects<br/>Clone Cells--drug effects<br/>Drug Resistance, Neoplasm<br/>Drug Screening Assays, Antitumor<br/>Fusion Proteins, bcr-abl--antagonists & inhibitors<br/>Gene Expression Regulation, Leukemic--drug effects<br/>Genes, abl<br/>HSP90 Heat-Shock Proteins--physiology<br/>Humans<br/>Hydrogen Peroxide--pharmacology<br/>Hydroquinones--adverse effects<br/>Imatinib Mesylate<br/>Lactams, Macrocyclic--adverse effects<br/>Mice<br/>Mutant Proteins--genetics<br/>Mutation, Missense<br/>Oxidative Stress--drug effects<br/>Piperazines--pharmacology<br/>Point Mutation<br/>Protein Kinase Inhibitors--adverse effects<br/>Protein Structure, Tertiary<br/>Proto-Oncogene Proteins c-akt--biosynthesis<br/>Proto-Oncogene Proteins c-bcr--biosynthesis<br/>Pyrimidines--pharmacology<br/>Reactive Oxygen Species<br/>Recombinant Fusion Proteins--genetics<br/>STAT5 Transcription Factor--biosynthesis<br/>Signal Transduction--drug effects<br/>Substrate Specificity<br/>Transfection