TY  - GEN
AU  - Dickinson,Gemma L
AU  - Rezaee,Saeed
AU  - Proctor,Nicholas J
AU  - Lennard,Martin S
AU  - Tucker,Geoffrey T
AU  - Rostami-Hodjegan,Amin
TI  - Incorporating in vitro information on drug metabolism into clinical trial simulations to assess the effect of CYP2D6 polymorphism on pharmacokinetics and pharmacodynamics: dextromethorphan as a model application
SN  - 0091-2700
PY  - 2007///0412
KW  - Antitussive Agents
KW  - blood
KW  - Clinical Trials as Topic
KW  - Computer Simulation
KW  - Cough
KW  - drug therapy
KW  - Cytochrome P-450 CYP2D6
KW  - genetics
KW  - Dextromethorphan
KW  - Dextrorphan
KW  - Models, Biological
KW  - Polymorphism, Genetic
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1177/0091270006294279
ER  -