Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote. [electronic resource]
- Virology May 2007
- 163-78 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
0042-6822
10.1016/j.virol.2006.11.025 doi
Amino Acid Sequence Antibodies, Viral CCR5 Receptor Antagonists Cell Line Cells, Cultured HIV Envelope Protein gp120--chemistry HIV Infections--blood HIV-1--genetics Heterozygote Humans Leukocytes, Mononuclear--virology Male Models, Molecular Molecular Sequence Data Mutation Peptide Fragments--chemistry Receptors, CCR5--genetics Receptors, CXCR4--antagonists & inhibitors Receptors, HIV--physiology Sequence Alignment Sequence Analysis, DNA Sequence Deletion