Smalley, Keiran S M

An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells. [electronic resource] - Cancer research Jan 2007 - 209-17 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0008-5472

10.1158/0008-5472.CAN-06-1538 doi


Apoptosis--drug effects
Glycogen Synthase Kinase 3--antagonists & inhibitors
Glycogen Synthase Kinase 3 beta
Humans
Melanoma--drug therapy
Mitochondria--drug effects
Organometallic Compounds--pharmacology
Protein Kinase Inhibitors--pharmacology
Ruthenium--chemistry
Tumor Suppressor Protein p53--biosynthesis
Up-Regulation