Abe, Kohtaro

Long-term inhibition of Rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice. [electronic resource] - Journal of cardiovascular pharmacology Dec 2006 - 280-5 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0160-2446

10.1097/01.fjc.0000248244.64430.4a doi


1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine--analogs & derivatives
Animals
Arterioles--drug effects
Blotting, Western
Disease Models, Animal
Hypertension, Pulmonary--physiopathology
Hypertrophy, Right Ventricular--physiopathology
Hypoxia--physiopathology
Intracellular Signaling Peptides and Proteins--antagonists & inhibitors
Lung--blood supply
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Nitric Oxide Synthase Type III--deficiency
Phosphorylation--drug effects
Protein Kinase Inhibitors--pharmacology
Protein Serine-Threonine Kinases--antagonists & inhibitors
Proto-Oncogene Proteins c-akt--metabolism
Time Factors
Up-Regulation--drug effects
rho-Associated Kinases