TY - GEN AU - Rohde,Jeffrey J AU - Pliushchev,Marina A AU - Sorensen,Bryan K AU - Wodka,Dariusz AU - Shuai,Qi AU - Wang,Jiahong AU - Fung,Steven AU - Monzon,Katina M AU - Chiou,William J AU - Pan,Liping AU - Deng,Xiaoqing AU - Chovan,Linda E AU - Ramaiya,Atul AU - Mullally,Mark AU - Henry,Rodger F AU - Stolarik,DeAnne F AU - Imade,Hovis M AU - Marsh,Kennan C AU - Beno,David W A AU - Fey,Thomas A AU - Droz,Brian A AU - Brune,Michael E AU - Camp,Heidi S AU - Sham,Hing L AU - Frevert,Ernst Uli AU - Jacobson,Peer B AU - Link,J T TI - Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors SN - 0022-2623 PY - 2007///0307 KW - 11-beta-Hydroxysteroid Dehydrogenase Type 1 KW - antagonists & inhibitors KW - Adamantane KW - analogs & derivatives KW - Animals KW - Cell Line KW - Humans KW - In Vitro Techniques KW - Mice KW - Microsomes, Liver KW - metabolism KW - Piperazines KW - chemical synthesis KW - Rats KW - Stereoisomerism KW - Structure-Activity Relationship KW - Tissue Distribution N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/jm0609364 ER -