TY - GEN AU - Tran,Tuan P AU - Ellsworth,Edmund L AU - Sanchez,Joseph P AU - Watson,Brian M AU - Stier,Michael A AU - Showalter,H D Hollis AU - Domagala,John M AU - Shapiro,Martin A AU - Joannides,E Themis AU - Gracheck,Stephen J AU - Nguyen,Dai Q AU - Bird,Paul AU - Yip,Judy AU - Sharadendu,Anurag AU - Ha,Chan AU - Ramezani,Saeed AU - Wu,Xiujuan AU - Singh,Rajeshwar TI - Structure-activity relationships of 3-aminoquinazolinediones, a new class of bacterial type-2 topoisomerase (DNA gyrase and topo IV) inhibitors SN - 0960-894X PY - 2007///0515 KW - Amines KW - chemistry KW - Anti-Bacterial Agents KW - chemical synthesis KW - DNA Gyrase KW - Gram-Positive Bacteria KW - drug effects KW - Inhibitory Concentration 50 KW - Quinazolinones KW - Structure-Activity Relationship KW - Topoisomerase II Inhibitors N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2006.12.005 ER -