Adrenal hyperplasia and adenomas are associated with inhibition of phosphodiesterase 11A in carriers of PDE11A sequence variants that are frequent in the population. [electronic resource]
- Cancer research Dec 2006
- 11571-5 p. digital
Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
0008-5472
10.1158/0008-5472.CAN-06-2914 doi
3',5'-Cyclic-GMP Phosphodiesterases Adenoma--enzymology Adrenocortical Hyperfunction--enzymology Base Sequence Carrier State Cell Line Codon, Nonsense Cushing Syndrome--enzymology DNA--genetics DNA Primers DNA, Neoplasm--genetics Gene Frequency Genetic Variation Genotype HeLa Cells Humans Kidney Loss of Heterozygosity Mutation Phosphoric Diester Hydrolases--genetics Pituitary Neoplasms--enzymology