TY - GEN AU - Chang,Yong S AU - Adnane,Jalila AU - Trail,Pamela A AU - Levy,Joan AU - Henderson,Arris AU - Xue,Dahai AU - Bortolon,Elizabeth AU - Ichetovkin,Marina AU - Chen,Charles AU - McNabola,Angela AU - Wilkie,Dean AU - Carter,Christopher A AU - Taylor,Ian C A AU - Lynch,Mark AU - Wilhelm,Scott TI - Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models SN - 0344-5704 PY - 2007///0522 KW - Actins KW - metabolism KW - Adenocarcinoma, Clear Cell KW - blood supply KW - Angiogenesis Inhibitors KW - therapeutic use KW - Animals KW - Antineoplastic Agents KW - Benzenesulfonates KW - Capillaries KW - pathology KW - Cell Line, Tumor KW - Female KW - Humans KW - Hypoxia KW - chemically induced KW - Immunohistochemistry KW - In Situ Nick-End Labeling KW - Kidney Neoplasms KW - Mice KW - Mice, Nude KW - Niacinamide KW - analogs & derivatives KW - Phenylurea Compounds KW - Platelet Endothelial Cell Adhesion Molecule-1 KW - immunology KW - Pyridines KW - Regional Blood Flow KW - drug effects KW - Sorafenib KW - Vascular Endothelial Growth Factor A N1 - Publication Type: Journal Article UR - https://doi.org/10.1007/s00280-006-0393-4 ER -