TY - GEN AU - Matal,Jaroslav AU - Orság,Jirí AU - Nekvindová,Jana AU - Anzenbacherová,Eva AU - Veinlichová,Alena AU - Anzenbacher,Pavel AU - Zídek,Zdenek AU - Holý,Antonín TI - Experimental approaches to studies on drug metabolism and drug interactions in man: interaction of acyclic nucleoside phosphonates with human liver cytochromes P450 and flavin-containing monooxygenase 3 SN - 0172-780X PY - 2007///0607 KW - Adenine KW - analogs & derivatives KW - Bacteria KW - ultrastructure KW - Cell Membrane KW - metabolism KW - Cytochrome P-450 Enzyme System KW - genetics KW - Drug Interactions KW - Humans KW - Liver KW - drug effects KW - Metabolic Detoxication, Phase I KW - Models, Biological KW - NADPH-Ferrihemoprotein Reductase KW - Organophosphonates KW - pharmacokinetics KW - Oxygenases KW - Research Design KW - Tenofovir KW - Transformation, Bacterial N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -