TY - GEN AU - Yamamoto,Noriyuki AU - Sawada,Hideyuki AU - Izumi,Yasuhiko AU - Kume,Toshiaki AU - Katsuki,Hiroshi AU - Shimohama,Shun AU - Akaike,Akinori TI - Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease SN - 0021-9258 PY - 2007///0326 KW - Acetylcysteine KW - analogs & derivatives KW - Active Transport, Cell Nucleus KW - drug effects KW - Adrenergic Agents KW - toxicity KW - Animals KW - Cell Nucleus KW - metabolism KW - Cysteine Proteinase Inhibitors KW - pharmacology KW - Dose-Response Relationship, Drug KW - Glutathione KW - biosynthesis KW - Hydrogen Peroxide KW - Imidazoles KW - Models, Biological KW - NF-E2 Transcription Factor KW - Oxidants KW - Oxidative Stress KW - Oxidopamine KW - PC12 Cells KW - Parkinson Disease KW - Proteasome Endopeptidase Complex KW - Proteasome Inhibitors KW - Pyridines KW - Rats KW - Reactive Oxygen Species KW - Ubiquitin KW - p38 Mitogen-Activated Protein Kinases KW - antagonists & inhibitors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M603712200 ER -