Cai, Ying <br/><br/>
Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation.  [electronic resource] 

 -  Free radical biology & medicine  Jan 2007 
 - 64-78 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0891-5849 
<br/><br/><label>Standard No.: </label>10.1016/j.freeradbiomed.2006.09.018  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>AMP-Activated Protein Kinases<br/>Aminoimidazole Carboxamide--analogs & derivatives<br/>Animals<br/>Apoptosis--physiology<br/>Blotting, Western<br/>Caspase 3--metabolism<br/>Cell Line<br/>Enzyme Activation<br/>Enzyme Inhibitors--pharmacology<br/>Glucose--pharmacology<br/>Hydrogen Peroxide--pharmacology<br/>Hypoglycemic Agents--metabolism<br/>Insulin--metabolism<br/>Insulin-Secreting Cells--metabolism<br/>JNK Mitogen-Activated Protein Kinases--metabolism<br/>Mice<br/>Mitochondria--metabolism<br/>Multienzyme Complexes--metabolism<br/>Palmitates--pharmacology<br/>Phosphorylation<br/>Protein Serine-Threonine Kinases--metabolism<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>RNA, Messenger--genetics<br/>Rats<br/>Reactive Oxygen Species--metabolism<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>Ribonucleotides--pharmacology