TY  - GEN
AU  - Patel,Meena V
AU  - Kolasa,Teodozyj
AU  - Mortell,Kathleen
AU  - Matulenko,Mark A
AU  - Hakeem,Ahmed A
AU  - Rohde,Jeffrey J
AU  - Nelson,Sherry L
AU  - Cowart,Marlon D
AU  - Nakane,Masaki
AU  - Miller,Loan N
AU  - Uchic,Marie E
AU  - Terranova,Marc A
AU  - El-Kouhen,Odile F
AU  - Donnelly-Roberts,Diana L
AU  - Namovic,Marian T
AU  - Hollingsworth,Peter R
AU  - Chang,Renjie
AU  - Martino,Brenda R
AU  - Wetter,Jill M
AU  - Marsh,Kennan C
AU  - Martin,Ruth
AU  - Darbyshire,John F
AU  - Gintant,Gary
AU  - Hsieh,Gin C
AU  - Moreland,Robert B
AU  - Sullivan,James P
AU  - Brioni,Jorge D
AU  - Stewart,Andrew O
TI  - Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction
SN  - 0022-2623
PY  - 2007///0223
KW  - Action Potentials
KW  - Administration, Oral
KW  - Animals
KW  - Benzamides
KW  - chemical synthesis
KW  - Biological Availability
KW  - Cell Line
KW  - Cyclic N-Oxides
KW  - Dogs
KW  - ERG1 Potassium Channel
KW  - Erectile Dysfunction
KW  - drug therapy
KW  - Ether-A-Go-Go Potassium Channels
KW  - physiology
KW  - Haplorhini
KW  - Humans
KW  - In Vitro Techniques
KW  - Male
KW  - Patch-Clamp Techniques
KW  - Purkinje Fibers
KW  - drug effects
KW  - Rats
KW  - Receptors, Dopamine D4
KW  - agonists
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm060662k
ER  -