Patel, Meena V <br/><br/>
Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction.  [electronic resource] 

 -  Journal of medicinal chemistry  Dec 2006 
 - 7450-65 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm060662k  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Action Potentials<br/>Administration, Oral<br/>Animals<br/>Benzamides--chemical synthesis<br/>Biological Availability<br/>Cell Line<br/>Cyclic N-Oxides--chemical synthesis<br/>Dogs<br/>ERG1 Potassium Channel<br/>Erectile Dysfunction--drug therapy<br/>Ether-A-Go-Go Potassium Channels--physiology<br/>Haplorhini<br/>Humans<br/>In Vitro Techniques<br/>Male<br/>Patch-Clamp Techniques<br/>Purkinje Fibers--drug effects<br/>Rats<br/>Receptors, Dopamine D4--agonists<br/>Structure-Activity Relationship