TY - GEN AU - Yang,Y AU - Ikezoe,T AU - Nishioka,C AU - Bandobashi,K AU - Takeuchi,T AU - Adachi,Y AU - Kobayashi,M AU - Takeuchi,S AU - Koeffler,H P AU - Taguchi,H TI - NFV, an HIV-1 protease inhibitor, induces growth arrest, reduced Akt signalling, apoptosis and docetaxel sensitisation in NSCLC cell lines SN - 0007-0920 PY - 2007///0130 KW - Adenocarcinoma KW - drug therapy KW - Animals KW - Antineoplastic Agents KW - therapeutic use KW - Apoptosis KW - drug effects KW - Carcinoma, Large Cell KW - Carcinoma, Non-Small-Cell Lung KW - Carcinoma, Squamous Cell KW - Cell Line, Tumor KW - Cell Proliferation KW - Cyclin-Dependent Kinase Inhibitor p21 KW - metabolism KW - Cyclin-Dependent Kinase Inhibitor p27 KW - Docetaxel KW - Down-Regulation KW - Drug Combinations KW - Glycogen Synthase Kinases KW - HIV Protease Inhibitors KW - pharmacology KW - Humans KW - Intracellular Signaling Peptides and Proteins KW - Lung Neoplasms KW - Male KW - Mice KW - Mice, Inbred BALB C KW - Mice, Nude KW - Nelfinavir KW - Proto-Oncogene Proteins c-akt KW - antagonists & inhibitors KW - Proto-Oncogene Proteins c-bcl-2 KW - RNA, Small Interfering KW - Signal Transduction KW - Taxoids KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/sj.bjc.6603435 ER -