Yang, Y <br/><br/>
NFV, an HIV-1 protease inhibitor, induces growth arrest, reduced Akt signalling, apoptosis and docetaxel sensitisation in NSCLC cell lines.  [electronic resource] 

 -  British journal of cancer  Dec 2006 
 - 1653-62 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0007-0920 
<br/><br/><label>Standard No.: </label>10.1038/sj.bjc.6603435  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenocarcinoma--drug therapy<br/>Animals<br/>Antineoplastic Agents--therapeutic use<br/>Apoptosis--drug effects<br/>Carcinoma, Large Cell--drug therapy<br/>Carcinoma, Non-Small-Cell Lung--drug therapy<br/>Carcinoma, Squamous Cell--drug therapy<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cyclin-Dependent Kinase Inhibitor p21--metabolism<br/>Cyclin-Dependent Kinase Inhibitor p27<br/>Docetaxel<br/>Down-Regulation<br/>Drug Combinations<br/>Glycogen Synthase Kinases--metabolism<br/>HIV Protease Inhibitors--pharmacology<br/>Humans<br/>Intracellular Signaling Peptides and Proteins--metabolism<br/>Lung Neoplasms--drug therapy<br/>Male<br/>Mice<br/>Mice, Inbred BALB C<br/>Mice, Nude<br/>Nelfinavir--pharmacology<br/>Proto-Oncogene Proteins c-akt--antagonists & inhibitors<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>RNA, Small Interfering--pharmacology<br/>Signal Transduction--drug effects<br/>Taxoids--therapeutic use<br/>Tumor Suppressor Protein p53--metabolism