TY - GEN AU - Nebert,Daniel W AU - Dalton,Timothy P TI - The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis SN - 1474-175X PY - 2007///0119 KW - Animals KW - Aryl Hydrocarbon Hydroxylases KW - metabolism KW - Biotransformation KW - Carcinogens, Environmental KW - pharmacokinetics KW - Cell Transformation, Neoplastic KW - drug effects KW - Cytochrome P-450 CYP1A1 KW - Cytochrome P-450 CYP1A2 KW - Cytochrome P-450 CYP1B1 KW - Cytochrome P-450 Enzyme System KW - genetics KW - DNA-Binding Proteins KW - Gene Expression Regulation, Enzymologic KW - Humans KW - Isoenzymes KW - Metabolic Networks and Pathways KW - Mice KW - Models, Biological KW - Neoplasms KW - chemically induced KW - Pharmacogenetics KW - Receptors, Aryl Hydrocarbon KW - Receptors, Cytoplasmic and Nuclear KW - Risk Assessment KW - Risk Factors KW - Signal Transduction KW - Transcription Factors N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review UR - https://doi.org/10.1038/nrc2015 ER -