TY - GEN AU - Di Marcotullio,Lucia AU - Ferretti,Elisabetta AU - Greco,Azzura AU - De Smaele,Enrico AU - Po,Agnese AU - Sico,Maria Anna AU - Alimandi,Maurizio AU - Giannini,Giuseppe AU - Maroder,Marella AU - Screpanti,Isabella AU - Gulino,Alberto TI - Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination SN - 1465-7392 PY - 2007///0109 KW - Animals KW - Cerebellar Neoplasms KW - genetics KW - Cerebellum KW - cytology KW - Down-Regulation KW - Gene Expression Regulation, Neoplastic KW - Hedgehog Proteins KW - metabolism KW - Humans KW - Kruppel-Like Transcription Factors KW - Medulloblastoma KW - Membrane Proteins KW - Mice KW - Nerve Tissue Proteins KW - Protein Processing, Post-Translational KW - RNA, Messenger KW - Repressor Proteins KW - Signal Transduction KW - Stem Cells KW - Transcription Factors KW - Ubiquitin-Protein Ligases KW - Ubiquitins KW - Zinc Finger Protein GLI1 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ncb1510 ER -