Di Marcotullio, Lucia <br/><br/>
Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination.  [electronic resource] 

 -  Nature cell biology  Dec 2006 
 - 1415-23 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1465-7392 
<br/><br/><label>Standard No.: </label>10.1038/ncb1510  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Cerebellar Neoplasms--genetics<br/>Cerebellum--cytology<br/>Down-Regulation<br/>Gene Expression Regulation, Neoplastic<br/>Hedgehog Proteins--metabolism<br/>Humans<br/>Kruppel-Like Transcription Factors--genetics<br/>Medulloblastoma--genetics<br/>Membrane Proteins--metabolism<br/>Mice<br/>Nerve Tissue Proteins--metabolism<br/>Protein Processing, Post-Translational<br/>RNA, Messenger--genetics<br/>Repressor Proteins--metabolism<br/>Signal Transduction<br/>Stem Cells--cytology<br/>Transcription Factors--genetics<br/>Ubiquitin-Protein Ligases--metabolism<br/>Ubiquitins--metabolism<br/>Zinc Finger Protein GLI1