TY  - GEN
AU  - Engel,Matthias
AU  - Hindie,Valerie
AU  - Lopez-Garcia,Laura A
AU  - Stroba,Adriana
AU  - Schaeffer,Francis
AU  - Adrian,Iris
AU  - Imig,Jochen
AU  - Idrissova,Leila
AU  - Nastainczyk,Wolfgang
AU  - Zeuzem,Stefan
AU  - Alzari,Pedro M
AU  - Hartmann,Rolf W
AU  - Piiper,Albrecht
AU  - Biondi,Ricardo M
TI  - Allosteric activation of the protein kinase PDK1 with low molecular weight compounds
SN  - 0261-4189
PY  - 2007///0126
KW  - 3-Phosphoinositide-Dependent Protein Kinases
KW  - Acetates
KW  - chemistry
KW  - Allosteric Regulation
KW  - Amino Acid Motifs
KW  - Binding Sites
KW  - Cells, Cultured
KW  - Drug Design
KW  - Enzyme Activation
KW  - Humans
KW  - Hydrophobic and Hydrophilic Interactions
KW  - Molecular Weight
KW  - Mutation
KW  - Phosphopeptides
KW  - pharmacology
KW  - Phosphorylation
KW  - Protein Conformation
KW  - Protein Serine-Threonine Kinases
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/sj.emboj.7601416
ER  -