Androstenediol inhibits the trauma-hemorrhage-induced increase in caspase-3 by downregulating the inducible nitric oxide synthase pathway. [electronic resource]
- Journal of applied physiology (Bethesda, Md. : 1985) Mar 2007
- 933-41 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
8750-7587
10.1152/japplphysiol.00919.2006 doi
Androstenediol--metabolism Animals Apoptosis--physiology Caspase 3--metabolism Down-Regulation Liver--enzymology Male NF-kappa B--metabolism Nitric Oxide Synthase Type II--metabolism Phosphatidylinositol 3-Kinases--metabolism Phosphorylation Proto-Oncogene Proteins c-akt--metabolism Proto-Oncogene Proteins c-bcl-2--metabolism Rats Rats, Sprague-Dawley Shock, Hemorrhagic--enzymology Tumor Suppressor Protein p53--metabolism Wounds and Injuries--enzymology