Brinkkoetter, P-T <br/><br/>
Atorvastatin interferes with activation of human CD4(+) T cells via inhibition of small guanosine triphosphatase (GTPase) activity and caspase-independent apoptosis.  [electronic resource] 

 -  Clinical and experimental immunology  Dec 2006 
 - 524-32 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0009-9104 
<br/><br/><label>Standard No.: </label>10.1111/j.1365-2249.2006.03217.x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Apoptosis--drug effects<br/>Atorvastatin<br/>Blotting, Western<br/>CD4-Positive T-Lymphocytes--drug effects<br/>Caspases--physiology<br/>Cell Cycle--drug effects<br/>Cell Proliferation--drug effects<br/>Cytokines--biosynthesis<br/>Dose-Response Relationship, Immunologic<br/>Enzyme Activation--drug effects<br/>Heptanoic Acids--pharmacology<br/>Humans<br/>Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology<br/>Interleukin-2 Receptor alpha Subunit--metabolism<br/>Lymphocyte Activation--drug effects<br/>Monomeric GTP-Binding Proteins--antagonists & inhibitors<br/>Pyrroles--pharmacology