TY  - GEN
AU  - Birch,Alan M
AU  - Kenny,Peter W
AU  - Oikonomakos,Nikos G
AU  - Otterbein,Ludovic
AU  - Schofield,Paul
AU  - Whittamore,Paul R O
AU  - Whalley,Dave P
TI  - Development of potent, orally active 1-substituted-3,4-dihydro-2-quinolone glycogen phosphorylase inhibitors
SN  - 0960-894X
PY  - 2007///0409
KW  - Animals
KW  - Biological Availability
KW  - Blood Proteins
KW  - metabolism
KW  - Caco-2 Cells
KW  - Chemical Phenomena
KW  - Chemistry, Physical
KW  - Crystallography, X-Ray
KW  - Enzyme Inhibitors
KW  - chemical synthesis
KW  - Glycogen Phosphorylase
KW  - antagonists & inhibitors
KW  - Hepatocytes
KW  - drug effects
KW  - Humans
KW  - Hypoglycemic Agents
KW  - pharmacology
KW  - Indicators and Reagents
KW  - Liver
KW  - enzymology
KW  - Magnetic Resonance Spectroscopy
KW  - Models, Molecular
KW  - Molecular Conformation
KW  - Muscle, Skeletal
KW  - Quinolines
KW  - Rabbits
KW  - Rats
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2006.10.037
ER  -