Birch, Alan M <br/><br/>
Development of potent, orally active 1-substituted-3,4-dihydro-2-quinolone glycogen phosphorylase inhibitors.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Jan 2007 
 - 394-9 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0960-894X 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2006.10.037  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Biological Availability<br/>Blood Proteins--metabolism<br/>Caco-2 Cells<br/>Chemical Phenomena<br/>Chemistry, Physical<br/>Crystallography, X-Ray<br/>Enzyme Inhibitors--chemical synthesis<br/>Glycogen Phosphorylase--antagonists & inhibitors<br/>Hepatocytes--drug effects<br/>Humans<br/>Hypoglycemic Agents--pharmacology<br/>Indicators and Reagents<br/>Liver--enzymology<br/>Magnetic Resonance Spectroscopy<br/>Models, Molecular<br/>Molecular Conformation<br/>Muscle, Skeletal--enzymology<br/>Quinolines--chemical synthesis<br/>Rabbits<br/>Rats