Price, Steve <br/><br/>
Identification and optimisation of a series of substituted 5-(1H-pyrazol-3-yl)-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Jan 2007 
 - 370-5 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0960-894X 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2006.10.048  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Biological Availability<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Computer Simulation<br/>Drug Evaluation, Preclinical<br/>Enzyme Inhibitors--chemical synthesis<br/>Histone Deacetylase Inhibitors<br/>Humans<br/>Hydroxamic Acids--chemical synthesis<br/>Indicators and Reagents<br/>Mice<br/>Neoplasm Transplantation<br/>Neoplasms, Experimental--drug therapy<br/>Pyrazoles--chemical synthesis<br/>Rats<br/>Structure-Activity Relationship<br/>Transplantation, Heterologous