Franciosi, Sonia <br/><br/>
Broad-spectrum effects of 4-aminopyridine to modulate amyloid beta1-42-induced cell signaling and functional responses in human microglia.  [electronic resource] 

 -  The Journal of neuroscience : the official journal of the Society for Neuroscience  Nov 2006 
 - 11652-64 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1529-2401 
<br/><br/><label>Standard No.: </label>10.1523/JNEUROSCI.2490-06.2006  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>4-Aminopyridine--pharmacology<br/>Amyloid beta-Peptides--pharmacology<br/>Animals<br/>Brain--cytology<br/>Calcium--metabolism<br/>Cells, Cultured<br/>Cyclooxygenase 2--metabolism<br/>Cytokines--genetics<br/>Drug Interactions<br/>Fetus<br/>Gene Expression--drug effects<br/>Guanosine 5'-O-(3-Thiotriphosphate)--pharmacology<br/>Humans<br/>Immunohistochemistry--methods<br/>Membrane Potentials--drug effects<br/>Membrane Proteins--metabolism<br/>Microglia--drug effects<br/>NF-kappa B--metabolism<br/>Neurons--chemistry<br/>Patch-Clamp Techniques--methods<br/>Peptide Fragments--pharmacology<br/>Potassium Channel Blockers--pharmacology<br/>Rats<br/>Reverse Transcriptase Polymerase Chain Reaction--methods<br/>Shaw Potassium Channels--genetics<br/>Signal Transduction--drug effects<br/>p38 Mitogen-Activated Protein Kinases--metabolism