Vulnerability of neurons with mitochondrial dysfunction to oxidative stress is associated with down-regulation of thioredoxin. [electronic resource]
- Neurochemistry international Jan 2007
- 379-85 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0197-0186
10.1016/j.neuint.2006.09.007 doi
Animals Blotting, Western Cells, Cultured Dose-Response Relationship, Drug Down-Regulation--physiology Electron Transport Complex IV--antagonists & inhibitors Enzyme Inhibitors--pharmacology Female Hydrogen Peroxide--pharmacology Membrane Potentials--drug effects Mice Mice, Inbred ICR Mitochondria--drug effects Neurons--physiology Oxidative Stress--physiology RNA--biosynthesis Reverse Transcriptase Polymerase Chain Reaction Sodium Azide--pharmacology Tetrazolium Salts Thiazoles Thioredoxins--biosynthesis Time Factors